220 compounds | Property logIGC50: 2-day Tetrahymena toxicity as log(IGC50) [log(mol/L)]
| ID | Name | logIGC50 | Details |
|---|---|---|---|
| 1 | 4-hydroxyphenylacetic acid | -1.500 | View |
| 2 | 1,3,5-trihydroxybenzene | -1.736 | View |
| 3 | 3-hydroxybenzyl alcohol | -1.957 | View |
| 4 | 4-hydroxybenzoic acid | -1.979 | View |
| 5 | 3-hydroxy-4-methoxybenzyl alcohol | -2.010 | View |
| 6 | 4-hydroxy-3-methoxybenzylamine | -2.030 | View |
| 7 | 2-hydroxybenzyl alcohol | -2.046 | View |
| 8 | 4-hydroxyphenethyl alcohol | -2.174 | View |
| 9 | 3-hydroxybenzoic acid | -2.186 | View |
| 10 | 4-hydroxybenzamide | -2.220 | View |
| 11 | 4-hydroxy-3-methoxybenzyl alcohol | -2.300 | View |
| 12 | resorcinol | -2.348 | View |
| 13 | 2,6-dimethoxyphenol | -2.402 | View |
| 14 | 2,4,6-tris-(dimethylaminomethyl)phenol | -2.480 | View |
| 15 | salicylic acid | -2.488 | View |
| 16 | 2-methoxyphenol | -2.490 | View |
| 17 | 5-methylresorcinol | -2.611 | View |
| 18 | 4-hydroxybenzylcyanide | -2.616 | View |
| 19 | 3-hydroxyacetophenone | -2.619 | View |
| 20 | 2-ethoxyphenol | -2.642 | View |
| 21 | 3-methoxyphenol | -2.674 | View |
| 22 | 4-hydroxyacetophenone | -2.698 | View |
| 23 | 3-ethoxy-4-methoxyphenol | -2.701 | View |
| 24 | 2-cresol | -2.705 | View |
| 25 | salicylamide | -2.758 | View |
| 26 | ethyl-4-hydroxy-3-methoxyphenylacetate | -2.770 | View |
| 27 | phenol | -2.792 | View |
| 28 | 4-cresol | -2.816 | View |
| 29 | 4-hydroxy-3-methoxyphenethyl alcohol | -2.820 | View |
| 30 | 3-acetamidophenol | -2.845 | View |
| 31 | 4-methoxyphenol | -2.857 | View |
| 32 | isovanillin | -2.859 | View |
| 33 | 4-hydroxy-3-methoxyacetophenone | -2.880 | View |
| 34 | 3,5-dimethoxyphenol | -2.908 | View |
| 35 | 2-hydroxyethylsalicylate | -2.920 | View |
| 36 | 3-cyanophenol | -2.936 | View |
| 37 | 3-cresol | -2.937 | View |
| 38 | methyl-3-hydroxybenzoate | -2.954 | View |
| 39 | vanillin | -2.970 | View |
| 40 | 4-hydroxy-3-methoxybenzonitrile | -2.970 | View |
| 41 | 4-ethoxyphenol | -3.013 | View |
| 42 | 3-ethoxy-4-hydroxybenzaldehyde | -3.015 | View |
| 43 | 4-fluorophenol | -3.017 | View |
| 44 | 2-cyanophenol | -3.034 | View |
| 45 | 5-fluoro-2-hydroxyacetophenone | -3.040 | View |
| 46 | 4-hydroxypropiophenone | -3.053 | View |
| 47 | 2,4-dimethylphenol | -3.070 | View |
| 48 | 2-hydroxyacetophenone | -3.078 | View |
| 49 | 2,5-dimethylphenol | -3.081 | View |
| 50 | methyl-4-hydroxybenzoate | -3.084 | View |
| 51 | 3-hydroxybenzaldehyde | -3.085 | View |
| 52 | 3,5-dimethylphenol | -3.113 | View |
| 53 | 2,3-dimethylphenol | -3.122 | View |
| 54 | 3,4-dimethylphenol | -3.122 | View |
| 55 | 4-chlororesorcinol | -3.125 | View |
| 56 | 2-ethylphenol | -3.160 | View |
| 57 | syringaldehyde | -3.168 | View |
| 58 | salicylhydrazide | -3.181 | View |
| 59 | 2-chlorophenol | -3.183 | View |
| 60 | 2-fluorophenol | -3.185 | View |
| 61 | 4-hydroxy-2-methylacetophenone | -3.190 | View |
| 62 | 4-ethylphenol | -3.205 | View |
| 63 | 3-ethylphenol | -3.228 | View |
| 64 | salicylaldoxime | -3.253 | View |
| 65 | 4-hydroxybenzaldehyde | -3.266 | View |
| 66 | 2,3,6-trimethylphenol | -3.277 | View |
| 67 | 2,4,6-trimethylphenol | -3.281 | View |
| 68 | 2-hydroxy-5-methylacetophenone | -3.310 | View |
| 69 | 2-bromophenol | -3.330 | View |
| 70 | 2-allylphenol | -3.334 | View |
| 71 | 5-bromo-2-hydroxybenzyl alcohol | -3.343 | View |
| 72 | 2,3,5-trimethylphenol | -3.360 | View |
| 73 | 2-vanillin | -3.377 | View |
| 74 | salicylhydroxamic acid | -3.379 | View |
| 75 | 3-fluorophenol | -3.381 | View |
| 76 | 2-chloro-5-methylphenol | -3.393 | View |
| 77 | 4-allyl-2-methoxyphenol | -3.420 | View |
| 78 | salicylaldehyde | -3.424 | View |
| 79 | 2,6-difluorophenol | -3.471 | View |
| 80 | 4-isopropylphenol | -3.473 | View |
| 81 | ethyl-3-hydroxybenzoate | -3.478 | View |
| 82 | 4-cyanophenol | -3.516 | View |
| 83 | 4-chlorophenol | -3.545 | View |
| 84 | 2-hydroxy-4-methoxyacetophenone | -3.550 | View |
| 85 | ethyl-4-hydroxybenzoate | -3.573 | View |
| 86 | 2-bromo-4-methylphenol | -3.599 | View |
| 87 | 2,4-difluorophenol | -3.604 | View |
| 88 | 3-isopropylphenol | -3.612 | View |
| 89 | 5-bromovanillin | -3.617 | View |
| 90 | α,α,α-trifluoro-4-cresol | -3.618 | View |
| 91 | methyl-4-methoxysalicylate | -3.620 | View |
| 92 | 4-propylphenol | -3.643 | View |
| 93 | 4-bromophenol | -3.680 | View |
| 94 | 2-chloro-4,5-dimethylphenol | -3.688 | View |
| 95 | 4-butoxyphenol | -3.701 | View |
| 96 | 4-chloro-2-methylphenol | -3.701 | View |
| 97 | 2-hydroxy-4,5-dimethylacetophenone | -3.707 | View |
| 98 | 3-(tert)-butylphenol | -3.730 | View |
| 99 | 2,6-dichlorophenol | -3.735 | View |
| 100 | 2-methoxy-4-propenylphenol | -3.750 | View |
| 101 | 3-chloro-5-methoxyphenol | -3.757 | View |
| 102 | 4-chloro-3-methylphenol | -3.796 | View |
| 103 | 2-isopropylphenol | -3.798 | View |
| 104 | 2,6-dichloro-4-fluorophenol | -3.804 | View |
| 105 | 4-iodophenol | -3.854 | View |
| 106 | 3-chlorophenol | -3.871 | View |
| 107 | 4-(tert)-butylphenol | -3.914 | View |
| 108 | 3,4,5-trimethylphenol | -3.932 | View |
| 109 | 4,6-dichlororesorcinol | -3.967 | View |
| 110 | 4-(sec)-butylphenol | -3.979 | View |
| 111 | 4-hydroxybenzophenone | -4.024 | View |
| 112 | 2,4-dichlorophenol | -4.036 | View |
| 113 | 4-benzyloxyphenol | -4.038 | View |
| 114 | 2,4,6-tribromoresorcinol | -4.060 | View |
| 115 | 4-chloro-3-ethylphenol | -4.081 | View |
| 116 | 2-phenylphenol | -4.094 | View |
| 117 | 3-iodophenol | -4.119 | View |
| 118 | 2,5-dichlorophenol | -4.125 | View |
| 119 | 3-chloro-4-fluorophenol | -4.131 | View |
| 120 | 3-bromophenol | -4.145 | View |
| 121 | 6-(tert)-butyl-2,4-dimethylphenol | -4.157 | View |
| 122 | 4-bromo-2,6-dimethylphenol | -4.167 | View |
| 123 | 4-chloro-3,5-dimethylphenol | -4.201 | View |
| 124 | 4-(tert)-pentylphenol | -4.229 | View |
| 125 | 4-bromo-3,5-dimethylphenol | -4.268 | View |
| 126 | 2,3-dichlorophenol | -4.276 | View |
| 127 | 4-bromo-6-chloro-2-cresol | -4.276 | View |
| 128 | 4-cyclopentylphenol | -4.292 | View |
| 129 | 2-(tert)-butylphenol | -4.295 | View |
| 130 | 2-(tert)-butyl-4-methylphenol | -4.301 | View |
| 131 | 5-pentylresorcinol | -4.306 | View |
| 132 | 3-phenylphenol | -4.351 | View |
| 133 | 4-phenylphenol | -4.393 | View |
| 134 | 2,4-dibromophenol | -4.398 | View |
| 135 | 2,4,6-trichlorophenol | -4.410 | View |
| 136 | 2-hydroxy-4-methoxybenzophenone | -4.420 | View |
| 137 | 3,5-dichlorosalicylaldehyde | -4.550 | View |
| 138 | 3,5-dichlorophenol | -4.569 | View |
| 139 | 3,5-di-(tert)-butylphenol | -4.638 | View |
| 140 | 4-hexyloxyphenol | -4.638 | View |
| 141 | 3,5-dibromosalicylaldehyde | -4.638 | View |
| 142 | 3,4-dichlorophenol | -4.745 | View |
| 143 | 4-bromo-2,6-dichlorophenol | -4.778 | View |
| 144 | 2,6-di-(tert)-butyl-4-methylphenol | -4.796 | View |
| 145 | 4-hexylresorcinol | -4.798 | View |
| 146 | 4-chloro-2-isopropyl-5-methylphenol | -4.854 | View |
| 147 | 2,4,6-tribromophenol | -5.030 | View |
| 148 | 4-heptyloxyphenol | -5.033 | View |
| 149 | 4-(tert)-octylphenol | -5.097 | View |
| 150 | 2,4,5-trichlorophenol | -5.097 | View |
| 151 | 3,5-diiodosalicylaldehyde | -5.340 | View |
| 152 | 2,3,5-trichlorophenol | -5.373 | View |
| 153 | nonylphenol | -5.468 | View |
| 154 | 2,4,6-trinitrophenol | -2.845 | View |
| 155 | 3,4-dinitrophenol | -3.266 | View |
| 156 | 2,3-dinitrophenol | -3.463 | View |
| 157 | 2,6-dinitrophenol | -3.539 | View |
| 158 | 2,6-dichloro-4-nitrophenol | -3.632 | View |
| 159 | 2,5-dinitrophenol | -3.950 | View |
| 160 | 2,4-dinitrophenol | -4.077 | View |
| 161 | 2,3,5,6-tetrafluorophenol | -4.167 | View |
| 162 | 2,6-dinitro-4-cresol | -4.229 | View |
| 163 | 2,6-dibromo-4-nitrophenol | -4.356 | View |
| 164 | pentafluorophenol | -4.638 | View |
| 165 | 2,6-diiodo-4-nitrophenol | -4.712 | View |
| 166 | 4,6-dinitro-2-cresol | -4.721 | View |
| 167 | 2,4-dichloro-6-nitrophenol | -4.745 | View |
| 168 | pentachlorophenol | -5.049 | View |
| 169 | 2,3,5,6-tetrachlorophenol | -5.222 | View |
| 170 | 3,4,5,6-tetrabromo-2-cresol | -5.574 | View |
| 171 | pentabromophenol | -5.664 | View |
| 172 | 2,3,4,5-tetrachlorophenol | -5.712 | View |
| 173 | 4-acetamidophenol | -2.180 | View |
| 174 | 3-aminophenol | -2.476 | View |
| 175 | 4-aminophenol | -2.924 | View |
| 176 | 2,4-diaminophenol | -3.127 | View |
| 177 | 3-methylcatechol | -3.280 | View |
| 178 | 2-amino-4-(tert)-butylphenol | -3.366 | View |
| 179 | 4-methylcatechol | -3.368 | View |
| 180 | 1,2,4-trihydroxybenzene | -3.439 | View |
| 181 | 5-amino-2-methoxyphenol | -3.450 | View |
| 182 | hydroquinone | -3.473 | View |
| 183 | catechol | -3.752 | View |
| 184 | 5-chloro-2-hydroxyaniline | -3.775 | View |
| 185 | 1,2,3-trihydroxybenzene | -3.850 | View |
| 186 | 6-amino-2,4-dimethylphenol | -3.886 | View |
| 187 | 2-aminophenol | -3.939 | View |
| 188 | 4-chlorocatechol | -4.061 | View |
| 189 | chlorohydroquinone | -4.262 | View |
| 190 | 4-amino-2-cresol | -4.307 | View |
| 191 | trimethylhydroquinone | -4.342 | View |
| 192 | 2,3-dimethylhydroquinone | -4.413 | View |
| 193 | 4-amino-2,3-dimethylphenol | -4.440 | View |
| 194 | bromohydroquinone | -4.678 | View |
| 195 | methylhydroquinone | -4.858 | View |
| 196 | phenylhydroquinone | -5.005 | View |
| 197 | 3,5-di-(tert)-butylcatechol | -5.109 | View |
| 198 | methoxyhydroquinone | -5.202 | View |
| 199 | 3-hydroxy-4-nitrobenzaldehyde | -3.270 | View |
| 200 | 5-hydroxy-2-nitrobenzaldehyde | -3.330 | View |
| 201 | 2-amino-4-nitrophenol | -3.475 | View |
| 202 | 3-nitrophenol | -3.506 | View |
| 203 | 4-methyl-2-nitrophenol | -3.571 | View |
| 204 | 4-hydroxy-3-nitrobenzaldehyde | -3.610 | View |
| 205 | 4-nitrosophenol | -3.654 | View |
| 206 | 2-nitroresorcinol | -3.658 | View |
| 207 | 2-nitrophenol | -3.670 | View |
| 208 | 4-methyl-3-nitrophenol | -3.740 | View |
| 209 | 2-chloromethyl-4-nitrophenol | -3.750 | View |
| 210 | 4-amino-2-nitrophenol | -3.879 | View |
| 211 | 3-fluoro-4-nitrophenol | -3.935 | View |
| 212 | 5-fluoro-2-nitrophenol | -4.125 | View |
| 213 | 4-nitrocatechol | -4.170 | View |
| 214 | 2-amino-4-chloro-5-nitrophenol | -4.174 | View |
| 215 | 4-nitrophenol | -4.420 | View |
| 216 | 2-chloro-4-nitrophenol | -4.585 | View |
| 217 | 4-chloro-6-nitro-3-cresol | -4.638 | View |
| 218 | 4-nitro-3-(trifluoromethyl)phenol | -4.652 | View |
| 219 | 3-methyl-4-nitrophenol | -4.729 | View |
| 220 | 4-chloro-2-nitrophenol | -5.053 | View |
Schüürmann, G.; Aptula, A. O.; Kühne, R.; Ebert, R. U. Stepwise Discrimination between Four Modes of Toxic Action of Phenols in the Tetrahymena pyriformis Assay. Chem. Res. Toxicol. 2003, 16, 974–987. https://doi.org/10.1021/tx0340504
Aptula, A. O.; Netzeva, T. I.; Valkova, I. V.; Cronin, M. T. D.; Schultz, T. W.; Kühne, R.; Schüürmann, G. Multivariate Discrimination between Modes of Toxic Action of Phenols. Quant. Struct.-Act. Relat. 2002, 21, 12–22. https://doi.org/10.1002/1521-3838(200205)21:1<12::AID-QSAR12>3.0.CO;2-M