Hewitt, M.; Madden, J.C.; Rowe, P.H.; Cronin, M.T.D. Structure-based modelling in reproductive toxicology: (Q)SARs for the placental barrier. SAR QSAR Environ. Res. 2007, 18, 57-76.

Compound

	ID:	57
	Name:	Pyrimethamine
	Description:
	Labels:
	CAS:	58-14-0
	InChi Code:	InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

Properties

CI: Clearance Index

Value	Source or prediction
1	experimental value
0.74056	Eq.3: QSAR model to predict placental transfer (Training set)