Cronin, M.T.D.; Bryant, S.E.; Dearden, J.C.; Schultz, T.W. Quantitative structure-activity study of the toxicity of benzonitriles to the ciliate Tetrahymena pyriformis. SAR QSAR Environ. Res. 1995, 3, 1, 1–13.

34 compounds | Property pIGC50: 48-h Tetrahymena toxicity as log(1/IGC50) [log(L/mmol)]

ID	Name	pIGC50	Details
1	4-cyanopyridine	-0.82	View
2	2-cyanopyridine	-0.79	View
3	3-cyanopyridine	-0.74	View
4	4-cyanoaniline	0.25	View
5	2-cyanoaniline	-0.50	View
6	3-cyanoaniline	-0.47	View
7	4-cyanophenol	0.52	View
8	2-cyanophenol	0.034	View
9	3-cyanophenol	-0.065	View
10	1-cyanonaphthalene	0.69	View
11	4-nitrobenzonitrile	0.57	View
12	2-nitrobenzonitrile	1.08	View
13	3-nitrobenzonitrile	0.45	View
14	2-tolunitrile	-0.24	View
15	3-tolunitrile	-0.25	View
16	1,2-dicyanobenzene	-0.34	View
17	4-tolunitrile	-0.10	View
18	4-biphenylcarbonitrile	1.24	View
19	4-bromobenzonitrile	0.29	View
20	benzonitrile	-0.52	View
21	2-chlorobenzonitrile	0.28	View
22	3-chlorobenzonitrile	-0.055	View
23	4-chlorobenzonitrile	0.00	View
24	4-fluorobenzonitrile	-0.26	View
25	4-methoxybenzonitrile	0.10	View
26	4-acetylbenzonitrile	-0.37	View
27	methyl-4-cyanobenzoate	-0.061	View
28	4-cyanobenzaldehyde	0.042	View
29	4-cyanobenzamide	-0.38	View
30	3-cyano-4,6-dimethyl-2-OH pyridine	-0.70	View
31	2-amino-5-chlorobenzonitrile	0.44	View
32	3-cyanobenzaldehyde	-0.019	View
33	3-methoxybenzonitrile	0.048	View
34	ethyl-4-cyanobenzoate	0.37	View

Bibliography

Cronin, M. T. D.; Bryant, S. E.; Dearden, J. C.; Schultz, T. W. Quantitative structure-activity study of the toxicity of benzonitriles to the ciliate Tetrahymena pyriformis. SAR QSAR Environ. Res. 1995, 3, 1–13. https://doi.org/10.1080/10629369508233989
Schultz, T. W.; Lin, D. T.; Wilke, T. S.; Arnold, L. M. Quantitative structure-activity relationships for the Tetrahymena pyriformis population growth endpoint: a mechanism of action approach. In Practical Applications of Quantitative Structure-Activity Relationships (QSAR) in Environmental Chemistry and Toxicology; Karcher, W.; Devillers, J., Eds.; Joint Research Centre; 1990.